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KMID : 0378019860290100161
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New Medical Journal
1986 Volume.29 No. 10 p.161 ~ p.165
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Clinical Effect of Reproterol . HCI(Broncard^(®)) on Bronchial Asthma
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張熙成/Chang, Hee Seoung
鄭垠澤/許玧/崔仁善/朴炅玉/Jeong, Eun Taek/Hur, Yun/Choi, In Seon/Park, Kyung Ok
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Abstract
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Reproterol(Broncard®), a monomolecular combination of catecholamine and theophylline, was evaluated for bronchodilatory and side effects in 29 patients with bronchial asthma or chronic obstructive pulmonary disease. A statistically significant bronchodilatory effect was obtained in an hour with 20mg oral dose and the response was the predominant volume response(ΔFEV1/ΔFVCAfter ingestion of the preparation for at least 7 days in doses of ´3x20 mg/day, adverse reactions generally expected from sympathomimetic stimulation, i.e., tremor, palpitation, dizziness, restlessness, etc. occurred in some patients and one case showed slight elevation of serum alanine aminotransferase.
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